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Mechanism of action
Ribociclib is a selective inhibitor of cyclin-dependent kinase (CDK) 4 and 6, resulting in 50% inhibition (IC50) values of 0.01 (4.3 ng/ml) and 0.039 μM (16.9 ng/ml) in biochemical assays, respectively. These kinases are activated upon binding to D-...
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Mélanome
Melanoma - traitement
Traitement du mélanome
Le diagnostic du mélanomeThe suspicious skin spot will first be cut away and sent to the laboratory for examination. If this examination shows that it is a melanoma, a second...
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Mélanome - Liens utiles
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